Psychotropic medications, particularly antipsychotics, can damage fibers in the Yoga poses to stretch back striatum, leading to the development of tremors, stiffness, or abnormal movements.
This raises Yoga poses to stretch back the possibility that NAC could protect patients from some of the adverse effects of treatment with antipsychotic medications such as haloperidol. SIDEBAR 2.2 THE STRIATUM AND BASAL GANGLIA The striatum, consisting of the caudate nucleus and the putamen, is part of the basal ganglia, anatomical structures within the cerebral cortex and midbrain with feedback loops to the substantia nigra, thalamus, and cerebral cortex.
This feedback system maintains and coordinates the tone of muscles that oppose one another to stabilize joint position, coordinate movements, or inhibit the tone of certain muscles during the initiation of movement. Damage to any part of this system results in loss of control with oscillatory movements appearing as tremors. For example, degeneration of dopaminergic fibers from the substantia nigra to the striatum leads to the tremors, stiffness, and other motor symptoms of parkinsonism. NAC has also been used to treat acetaminophen Tylenol overdose and to reduce the risk of respiratory infections and flu.