Outperformed placebo on all secondary measures: clinical global impression of Legs-Up-the-Wall Yoga Pose change, Erlangen anxiety tension and aggression scale, list of complaints, and the patient' Legs-Up-the-Wall Yoga Pose s global rating of change Woelk, Arnoldt, Kieser, & Hoerr, 2007. In a 22-week randomized controlled trial of 400 patients with dementia and neuropsychiatric features, patients were given either 240 mg/day EGb 761 or placebo.
Of those treated with ginkgo, 67. 5% had significant improvement in cognitive function versus 6.Among the caregivers of patients on ginkgo, 36% reported less distress related to the patient's symptoms compared with a 4% increase for those on placebo.
Scores on the Neuropsychiatric Inventory dropped significantly in the ginkgo group compared to an increase in the placebo group.
The largest differences in scores were improvements in apathy/indifference, anxiety, irritability/lability, depression/dysphoria, and sleep/nighttime behavior Scripnikov, Khomenko, & Napryeyenko, 2007. Special extract EGb 761 has shown positive effects on anxiety in well-designed controlled trials.